Application of the total internal reflection method for the study of liquid-phase medium based on botulinum toxin
https://doi.org/10.17586/0021-3454-2022-65-5-343-349
Abstract
Application of the total internal reflection method for the study of liquid-phase media based on botulinum toxin is considered. A comparative analysis of these drugs is carried out. Structural and functional scheme, as well as technical and operational characteristics of the developed refractometric system are presented. Botulinum toxinbased drugs Botox, Xeomin, and Dysport are used as objects of research. Experimental results of measurements of the concentration dependences of the refractive index in these preparations are obtained. It is shown that temperature dependences for Botox, Xeomin, and Dysport at various concentrations make it possible to change the algorithm of temperature correction of refractometric data.
About the Authors
O. V. Gromov
University under the Inter-Parliamentary Assembly of EurAsEC
Russian Federation
Russian Federation
Oleg V. Gromov — PhD, Associate Professor; Department of Vehicle Service.
St. Petersburg
R. B. Guliyev
University under the Inter-Parliamentary Assembly of EurAsEC
Russian Federation
Russian Federation
Ramiz B. Guliyev — PhD, Department of Mathematics and Information Technologies.
St. Petersburg
T. A. Chernyak
St. Petersburg State University of Aerospace Instrumentation
Russian Federation
Russian Federation
Tatyana A. Chernyak — PhD, Associate Professor, Department of Higher Mathematics and Mechanics.
St. Petersburg
E. E. Maiorov
St. Petersburg State University of Aerospace Instrumentation
Russian Federation
Russian Federation
Evgeny E. Maiorov — PhD, Associate Professor; Department of Applied Mathematics.
St. Petersburg
A. V. Dagaev
Ivangorod Humanitarian and Technical Institute, Branch of St. Petersburg State University of Aerospace Instrumentation
Russian Federation
Russian Federation
Alexander V. Dagaev — PhD; Ivangorod Humanitarian and Technical Institute, Department of Applied Mathematics, Informatics, and Customs Information Technologies.
Ivangorod
I. S. Tayurskaya
St. Petersburg University of Management Technologies and Economics
Russian Federation
Russian Federation
Irina S. Tayurskaya — PhD, Associate Professor, Department of Information Technology and Mathematics.
St. Petersburg
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Review
For citations:
Gromov O.V., Guliyev R.B., Chernyak T.A., Maiorov E.E., Dagaev A.V., Tayurskaya I.S. Application of the total internal reflection method for the study of liquid-phase medium based on botulinum toxin. Journal of Instrument Engineering. 2022;65(5):343-349. (In Russ.) https://doi.org/10.17586/0021-3454-2022-65-5-343-349
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